Recombinant Cytokeratin 18 antibody (full length)

Catalog No. ABIN6654634

The Rabbit Monoclonal anti-Cytokeratin 18 antibody is suitable to detect Cytokeratin 18 in samples from Human. It has been validated for WB, IF, FACS and IHC (p).

Quick Overview for Recombinant Cytokeratin 18 antibody (full length) (ABIN6654634)

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Cytokeratin 18 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: KRT18-2819R

Product Details anti-Cytokeratin 18 Antibody

Binding Specificity: full length

Purpose: Recombinant Cytokeratin 18 Antibody (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogen: Full length recombinant human protein was used as the immunogen for the recombinant Cytokeratin 18 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Cytokeratin 18 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Cytokeratin 18 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Cytokeratin 18

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Alternative Name: Cytokeratin 18

Background: This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

UniProt: P05783

Pathways: Apoptosis, Caspase Cascade in Apoptosis