SAP30 antibody

Catalog No. ABIN6655576

Product Details anti-SAP30 Antibody

Target: SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAP30 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): Cross reactivity with SAP30 from species other than human not tested.

Purification: Anti-SAP30 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Immunogen:

Immunogen: Anti-SAP30 Antibody was produced in rabbits by repeated immunizations with a full length protein of human SAP30 containing a His tag.

Immunogen Type: Native Protein

Application Details

Application Notes:

Application Note: Anti-SAP30 Antibody is suitable in western blot. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 23.3 kDa in the appropriate cell lysate or extract.

Western Blot Dilution: 1:1,000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

0.01 % (w/v) Sodium Azide

Stabilizer: None

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Target Details for SAP30

Target: SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))

Alternative Name: SAP30 (SAP30 Products)

Synonyms: 30kDa antibody, Sin3A associated protein 30 antibody, sin3 associated polypeptide antibody, Sin3A associated protein 30kDa S homeolog antibody, SAP30 antibody, Sap30 antibody, sap30.S antibody

Background:

Synonyms: Histone deacetylase complex subunit SAP30, 30 kDa Sin3-associated polypeptide, Sin3 corepressor complex subunit SAP30, Sin3-associated polypeptide p30

Background: SAP30 is a component of the histone deacetylase complex, which also includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48. Histone acetylation and deacetylation play a key role in the regulation of eukaryotic gene expression. This complex only deacetylates core histone octamers, and is not able to deacetylate nucleosomal histones. Anti-SAP30 Antibody is ideal for research in Gene Expression and Epigenetics.

Gene Name: SAP30

Gene ID: 8819

NCBI Accession: NP_003885

UniProt: O75446