SAP30 antibody (AA 140-220)

Catalog No. ABIN7231250

The Rabbit Polyclonal anti-SAP30 antibody is suitable to detect SAP30 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for SAP30 antibody (AA 140-220) (ABIN7231250)

Target: SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAP30 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SAP30 Antibody

Binding Specificity: AA 140-220

Purpose: Rabbit Anti-SAP30 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SAP30 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SAP30 protein at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SAP30

Target: SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))

Alternative Name: SAP30

Background: Histone deacetylase complex subunit SAP30, 30 kDa Sin3-associated polypeptide, Sin3 corepressor complex subunit SAP30, Sin3-associated polypeptide p30SAP30 (Sin3A Associated Protein 30) is a Protein Coding gene. Among its related pathways are Chromatin organization and Macrophage Differentiation and Growth Inhibition by METS. Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of SAP30 is located on chromosome 3.

Molecular Weight: 24kD

Gene ID: 8819

UniProt: O75446