KDM1B antibody (Internal Region, N-Term)
-
- Target See all KDM1B Antibodies
- KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))
-
Binding Specificity
- Internal Region, N-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This KDM1B antibody is un-conjugated
-
Application
- ELISA
- Cross-Reactivity (Details)
- Cross reactivity with KDM1B from other species not tested.
- Purification
- Anti-KDM1B Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
- Immunogen
-
Immunogen: Anti-KDM1B Antibody was produced in rabbits by repeated immunizations with two different synthetic peptides containing a sequence from the N-terminus and internal region of the human KDM1B protein.
Immunogen Type: Peptide
- Top Product
- Discover our top product KDM1B Primary Antibody
-
-
- Application Notes
-
Application Note: Anti-KDM1B Antibody is suitable for ELISA. Specific conditions for reactivity should be optimized by the end user.
ELISA Dilution: 1:500
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
-
0.01 % (w/v) Sodium Azide
Stabilizer: None
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- RT,4 °C,-20 °C
- Storage Comment
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
- Target
- KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))
- Alternative Name
- KDM1B (KDM1B Products)
- Synonyms
- AOF1 antibody, C6orf193 antibody, LSD2 antibody, bA204B7.3 antibody, dJ298J15.2 antibody, 4632428N09Rik antibody, AI482520 antibody, Aof1 antibody, lysine demethylase 1B antibody, lysine-specific histone demethylase 1B antibody, lysine (K)-specific demethylase 1B antibody, KDM1B antibody, LOC577549 antibody, kdm1b antibody, Kdm1b antibody
- Background
-
Synonyms: Lysine-specific histone demethylase 1B, Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2, AOF1, C6orf193, LSD2
Background: KDM1B is a histone demethylase that demethylates lysine 4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. KDM1B is able to demethylate both mono- and di-methylated lysine 4 of histone H3, but has no effect on tri-methylated lysine 4, mono-, di- or tri-methylated lysine 9, mono-, di- or tri-methylated lysine 27, mono-, di- or tri-methylated lysine 36 of histone H3, or on mono-, di- or tri-methylated lysine 20 of histone H4. KDM1B is also required for de novo DNA methylation of a subset of imprinted genes during oogenesis. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Anti-KDM1B is ideal for research in Epigenetics and Gene Expression.
Gene Name: KDM1B
- Gene ID
- 221656
- NCBI Accession
- NP_694587
- UniProt
- Q8NB78
- Pathways
- Warburg Effect
-