LAMP1 antibody

Catalog No. ABIN6656061

Supplier Product No.: 200-301-x13

This Mouse Monoclonal antibody specifically detects LAMP1 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for LAMP1 antibody (ABIN6656061)

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LAMP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 5H6

Product Details anti-LAMP1 Antibody

Supplier Product No.: 200-301-x13

Supplier: Rockland

Purpose: LAMP1 Antibody

Purification: Anti-LAMP1 Antibody was purified from tissue culture supernatant by protein G chromatography.

Sterility: Sterile filtered

Immunogen: Anti-LAMP1 Antibody was produced in mice by repeated immunizations with a recombinant full length human LAMP1 expressed in and purified from E. coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA_Dilution: 1:50,000

Immunohistochemistry_Dilution: 1:2000

Western_Blot_Dilution: 1:5000

Other: ICC: 1:500-1:2000

Comment:

Anti-LAMP1 Antibody is tested for Western Blot, immunohistochemistry, and Immunocytochemistry, and it is specific for the ~100 kDa LAMP1 protein. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.

Expiry Date: 12 months

Target Details for LAMP1

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Alternative Name: Lamp1

Background:

Synonyms: Lysosome-associated membrane glycoprotein 1, LAMP-1, Lysosome-associated membrane protein 1, CD107 antigen-like family member A, CD_antigen=CD107a

Background: Lysosomal Associated Membrane Protein1 (LAMP1) is a protein that is localized primarily in lysosomes but may also be present on late endosomes and the plasma membrane. LAMP1 antibodies are therefore widely used as lysosome markers. It has recently been suggested that lysosomes are activated in microglia in the progression of multiple system atrophy (MSA) and thus play a key role in its pathology. LAMP1 Antibody is ideal for researchers interested in neuroscience research.

Gene Name: LAMP1

Gene ID: 3916

NCBI Accession: NP_005552

UniProt: P11279

Pathways: Autophagy