GABRB3 antibody (C-Term)

Catalog No. ABIN6657744

Product Details anti-GABRB3 Antibody

Target: GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))

Binding Specificity: C-Term

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This GABRB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: Anti-GABA-A receptor Beta3 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with GABA-A receptor Beta3 from human, mouse, and rat based on 100% homology with the immunizing sequence. No cross-reactivity against GABA-A-R-Beta 2 or -Beta1. Cross-reactivity with GABA-A receptor Beta3 from other sources has not been determined. Ion Channels research.

Immunogen:

Immunogen: GABA-A Receptor Beta3 Antibody was produced in mice by repeated immunizations with fusion protein corresponding to a near c-terminal region of mouse GABA-A_r Beta3.

Immunogen Type: Recombinant Protein

Clone: S87-25

Isotype: IgG1

Application Details

Application Notes:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-GABA-A receptor Beta3 Antibody is suitable for use in WB and IF microscopy. Expect a band approximately ~55 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: 1 μg/mL

IF Microscopy Dilution: 1.0-10 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

0.09 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Target Details for GABRB3

Target: GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))

Alternative Name: GABA-A Receptor Beta3 (GABRB3 Products)

Synonyms: GABRB3 antibody, eca5 antibody, LOC100230475 antibody, ECA5 antibody, A230092K12Rik antibody, AW049585 antibody, Cp1 antibody, Gabrb-3 antibody, beta3 antibody, gamma-aminobutyric acid type A receptor beta3 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, beta 3 antibody, gamma-aminobutyric acid type A receptor beta 3 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 antibody, GABRB3 antibody, gabrb3 antibody, Gabrb3 antibody

Background:

Synonyms: Gabrb3, GABA(A) receptor subunit beta3, Gamma-aminobutyric acid receptor subunit beta-3

Background: The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features. GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain.

Gene Name: Gabrb3

Gene ID: 14402

NCBI Accession: NP_032097

UniProt: P63080

Pathways: Sensory Perception of Sound