ADCY3 antibody (C-Term)

Catalog No. ABIN6658102

Product Details anti-ADCY3 Antibody

Target: ADCY3 (Adenylate Cyclase 3 (ADCY3))

Binding Specificity: C-Term

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: Anti-Adenylate Cyclase III antibody is directed to rat adenylate cyclase III protein. Anti-Adenylate Cyclase III was purified by affinity purification.

Immunogen:

Immunogen: Anti-Adenylate Cyclase III Antibody was produced in rabbit by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the C-terminal region of rat adenylate cyclase III conjugated to KLH.

Immunogen Type: Peptide

Isotype: IgG

Application Details

Application Notes:

Application Note: Anti-Adenylate Cyclase III antibody is suitable for Western Blots and Immunofluorescence. Expect a band at approximately ~160/200 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

ELISA Dilution: 1:20,000

Western Blot Dilution: 1:2000

IF Microscopy Dilution: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

0.01 % (w/v) Sodium Azide/p>

Stabilizer: None

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,-20 °C

Storage Comment: Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.

Target Details for ADCY3

Target: ADCY3 (Adenylate Cyclase 3 (ADCY3))

Alternative Name: Adenylate Cyclase III (ADCY3 Products)

Synonyms: ADCY8 antibody, adcy3 antibody, si:ch211-153j24.5 antibody, Adcy3 antibody, ADCY3 antibody, Amac3 antibody, GB11637 antibody, AC3 antibody, mKIAA0511 antibody, adenylate cyclase 3 antibody, adenylate cyclase 3b antibody, DnaJ heat shock protein family (Hsp40) member C27 antibody, ADCY3 antibody, adcy3b antibody, dnajc27 antibody, Ac3 antibody, Adcy3 antibody

Background:

Synonyms: ATP pyrophosphate-lyase 3, Adenylate cyclase type III, AC-III, Adenylate cyclase olfactive type, Adenylyl cyclase 3, AC3

Background: Adenylate cyclase is the enzyme which produces the ""second messenger"" signaling molecule, cAMP from ATP. Type III adenylate cyclase is localized to the membranes surrounding neuronal cilia. Much is currently unknown about the function of primary cilia in vertebrates, however, recent work has begun to explore their role in neuronal signaling and neurogenesis. Adenylate Cyclase III Antibody is ideal for researchers interested in cell signaling and neuroscience research.

Gene Name: ADCY3

Gene ID: 64508

NCBI Accession: NP_570135

UniProt: P21932

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma