PICK1 antibody

Catalog No. ABIN6658111

Product Details anti-PICK1 Antibody

Target: PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This PICK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: Anti-PICK1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with PICK1 from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with PICK1 from other sources has not been determined. Scaffolds research.

Immunogen:

Immunogen: PICK1 Antibody was produced in mice by repeated immunizations raised against a fusion protein rat PICK1.

Immunogen Type: Recombinant Protein

Clone: S20-8

Isotype: IgG2a

Application Details

Application Notes:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-PICK1 Antibody is suitable for use in WB, IHC and IP. Expect a band approximately ~45 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Immunoprecipitation Dilution: User Optimized

Western Blot Dilution: 1 μg/mL

IF Microscopy Dilution: 1.0-10 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Storage: RT,4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Target Details for PICK1

Target: PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

Alternative Name: PICK1 (PICK1 Products)

Synonyms: PICK antibody, PRKCABP antibody, Prkcabp antibody, prkcabp antibody, MGC131295 antibody, PICK1 antibody, DKFZp470L2127 antibody, protein interacting with PRKCA 1 antibody, protein interacting with C kinase 1 antibody, protein interacting with PRKCA 1 L homeolog antibody, PICK1 antibody, Pick1 antibody, pick1 antibody, pick1.L antibody

Background:

Synonyms: PRKCA, protein interacting with PRKCA1, PRKCA-binding protein, Protein interacting with C kinase 1, Protein kinase C-alpha-binding protein, Pick1, Prkcabp

Background: PRKCA-binding protein is a protein that is encoded by the Pick1 gene. The protein encoded by this gene contains a PSD domain, which interacts with protein kinase C, alpha. The protein functions as an adaptor that binds to and organizes subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, and non-voltage gated sodium channels. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner.

Gene Name: Pick1