PICK1 antibody (AA 1-200)

Catalog No. ABIN7164283

Product Details anti-PICK1 Antibody

Target: PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

Binding Specificity: AA 1-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PICK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human PRKCA-binding protein (1-200AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PICK1

Target: PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

Alternative Name: PICK1 (PICK1 Products)

Synonyms: PICK antibody, PRKCABP antibody, Prkcabp antibody, prkcabp antibody, MGC131295 antibody, PICK1 antibody, DKFZp470L2127 antibody, protein interacting with PRKCA 1 antibody, protein interacting with C kinase 1 antibody, protein interacting with PRKCA 1 L homeolog antibody, PICK1 antibody, Pick1 antibody, pick1 antibody, pick1.L antibody

Background:

Background: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.

Aliases: dJ1039K5 antibody, MGC15204 antibody, OTTHUMP00000028509 antibody, PICK 1 antibody, Pick1 antibody, PICK1_HUMAN antibody, PRKCA binding protein antibody, PRKCA-binding protein antibody, PRKCABP antibody, Protein interacting with C kinase 1 antibody, Protein interacting with PRKCA antibody, Protein interacting with PRKCA 1 antibody, Protein kinase C alpha binding protein antibody, Protein kinase C-alpha-binding protein antibody, Protein that interacts with C kinase 1 antibody

UniProt: Q9NRD5