HTR7 antibody (N-Term)

Catalog No. ABIN6658112

Supplier Product No.: 200-401-i13

The Rabbit Polyclonal anti-HTR7 antibody (ABIN6658112) specifically detects HTR7 in WB, IF and FACS. The antibody is reactive with Rat samples.

Quick Overview for HTR7 antibody (N-Term) (ABIN6658112)

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-HTR7 Antibody

Binding Specificity: N-Term

Supplier Product No.: 200-401-i13

Supplier: Rockland

Purpose: Serotonin Receptor 7 Antibody

Cross-Reactivity (Details): A BLAST analysis was used to suggest cross-reactivity with Anti-Serotonin Receptor 7 from human, mouse, dog and rat based on 100 % homology with the immunizing sequence.

Purification: Anti-Serotonin Receptor 7 Antibody was purified by Protein G chromatography.

Immunogen: Serotonin Receptor 7 Antibody was produced from whole rabbit serum prepared by repeated immunizations with amino acids near the n-terminus of rat protein 5-HT7R.

Isotype: IgG

Application Details

Application Notes: Optional[Neutralization_Dilution]: 1:500-1:1000

Comment:

Anti-Serotonin Receptor 7 Antibody is tested for use in FLOW, IF/ICC, and WB. Expect a band approximately 45-50kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.05 % BSA

Preservative: 0.05 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for HTR7

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Alternative Name: Serotonin Receptor 7

Background:

Synonyms: 5-HT-X, Serotonin receptor 7

Background: Anti-Serotonin Receptor 7 antibody detects rat, human and dog Serotonin Receptor 7. Receptors for serotonin (5-hydroxytryptamine, 5-HT) are classified into seven major classes (5-HTR1-7), based on structural, functional and pharmacological criteria. The 5-HT7 receptor (5-HT7R) is a seven-transmembrane-domain G-protein-coupled receptor that has important roles in regulating diverse biological process in the central and peripheral nervous systems. Receptors for serotonin (5-hydroxytryptamine, 5-HT) are classified into seven major classes (5-HT1-7), based on structural, functional and pharmacological criteria. Sequence alignment shows a high degree of interspecies 5-HT7R homology (>90 % ), and a low homology with other 5-HTRs. Anti-Serotonin Receptor 7 is ideal for researchers interested in Neurobiology research.

Gene Name: Htr7

Gene ID: 103694905

NCBI Accession: NP_075227

UniProt: P32305

Pathways: JAK-STAT Signaling