HTR7 antibody (N-Term)

Catalog No. ABIN6658112

Product Details anti-HTR7 Antibody

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Binding Specificity: N-Term

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR7 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: Anti-Serotonin Receptor 7 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-Serotonin Receptor 7 from human, mouse, dog and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Serotonin Receptor 7 from other sources has not been determined.

Immunogen:

Immunogen: Serotonin Receptor 7 Antibody was produced from whole rabbit serum prepared by repeated immunizations with amino acids near the n-terminus of rat protein 5-HT7R.

Immunogen Type: Peptide

Isotype: IgG

Application Details

Application Notes:

Application Note: Anti-Serotonin Receptor 7 Antibody is suitable for use in IF/ICC and WB. Expect a band approximately 45-50 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.05 % BSA

0.05 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Target Details for HTR7

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Alternative Name: Serotonin Receptor 7 (HTR7 Products)

Synonyms: 5-HT7 antibody, 5-HT-dro antibody, 5-HT-dro1 antibody, 5-HT7Dro antibody, 5-HT[7]Dro antibody, 5-HT[[7Dro]] antibody, 5-HT[[7]] antibody, 5-HT[[7]]Dro antibody, 5-HT[[dro1]] antibody, 5-HTdro1 antibody, 5HT-7 antibody, 5HT-R1 antibody, 5HT-dro antibody, 5HT-dro1 antibody, 5HT[[7Dro]] antibody, 5htdror antibody, CG12073 antibody, DRO1 antibody, Dm5HTdro1 antibody, Dmel\\CG12073 antibody, 5Ht7 antibody, 5HT7 antibody, htr7-A antibody, 5-hydroxytryptamine receptor 7 antibody, 5-hydroxytryptamine (serotonin) receptor 7 antibody, 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled antibody, 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled L homeolog antibody, HTR7 antibody, 5-HT7 antibody, LOC752003 antibody, Htr7 antibody, htr7.L antibody

Background:

Synonyms: 5-HT-X, Serotonin receptor 7

Background: Anti-Serotonin Receptor 7 antibody detects rat, human and dog Serotonin Receptor 7. Receptors for serotonin (5-hydroxytryptamine, 5-HT) are classified into seven major classes (5-HTR1-7), based on structural, functional and pharmacological criteria. The 5-HT7 receptor (5-HT7R) is a seven-transmembrane-domain G-protein-coupled receptor that has important roles in regulating diverse biological process in the central and peripheral nervous systems. Receptors for serotonin (5-hydroxytryptamine, 5-HT) are classified into seven major classes (5-HT1-7), based on structural, functional and pharmacological criteria. Sequence alignment shows a high degree of interspecies 5-HT7R homology (>90 % ), and a low homology with other 5-HTRs. Anti-Serotonin Receptor 7 is ideal for researchers interested in Neurobiology research.

Gene Name: Htr7

Gene ID: 65032

NCBI Accession: NP_075227

UniProt: Q9NQC3

Pathways: JAK-STAT Signaling