Tyrosine Hydroxylase antibody

Quick Overview for Tyrosine Hydroxylase antibody (ABIN6658148)
Target
See all Tyrosine Hydroxylase (TH) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Supplier Product No.
- 600-401-c98
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Supplier
- Rockland
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Purpose
- Tyrosine Hydroxylase Antibody
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Cross-Reactivity (Details)
- Anti-Tyrosine Hydroxylase Antibody is directed against rat Tyrosine Hydroxylase protein.
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Purification
- The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
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Immunogen
- Anti-Tyrosine Hydroxylase Antibody was produced by repeated immunizations with SDS-denatured, native rat tyrosine hydroxylase purified from pheochromocytoma.
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Isotype
- IgG
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Application Notes
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Immunohistochemistry_Dilution: 1:1000
IF_Microscopy_Dilution: 1:1000
Western_Blot_Dilution: 1:1000
Other: User optimized
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Comment
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Anti-Tyrosine Hydroxylase (Rabbit) antibody is tested for use in Western Blotting and IHC/ICC and suitable for IF. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 60 kDa in size corresponding to the tyrosine hydroxylase proteins in the appropriate cell lysate or extract.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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Expiry Date
- 12 months
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- Tyrosine Hydroxylase (TH)
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Alternative Name
- Tyrosine Hydroxylase
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Background
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Synonyms: Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH
Background: Tyrosine Hydroxylase Antibody detects Tyrosine Hydroxylase protein. Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse. TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling.
Gene Name: TH
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Gene ID
- 25085
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NCBI Accession
- NP_036872
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UniProt
- P04177
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Pathways
- Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
Target
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