DLG4 antibody (N-Term)

Catalog No. ABIN6658210

Supplier Product No.: 612-401-e19

The Rabbit Polyclonal anti-DLG4 antibody has been validated for WB. It is suitable to detect DLG4 in samples from Rat.

Quick Overview for DLG4 antibody (N-Term) (ABIN6658210)

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLG4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DLG4 Antibody

Binding Specificity: N-Term

Supplier Product No.: 612-401-e19

Supplier: Rockland

Purpose: PSD95 Antibody

Cross-Reactivity (Details): This antibody is directed against PSD 95 proteins.

Purification: Anti-PSD-95 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-PSD-95 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.

Isotype: IgG

Application Details

Application Notes: Optional[Neutralization_Dilution]: 1:1000

Comment:

Anti-PSD 95 (Rabbit) antibody is tested for use in Western Blotting. Expect a band of approximately 95 kDa in size corresponding to PSD-95 protein in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  Aliquot contents and freeze at -20° C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for DLG4

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Alternative Name: PSD-95

Background:

Synonyms: Disks large homolog 4, Postsynaptic density protein 95, Synapse-associated protein 90, SAP-90, SAP90

Background: PSD-95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses. Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation. Anti-PSD-95 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: DLG4

Gene ID: 29495

UniProt: P31016

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity