CCR2 antibody (Biotin)

Catalog No. ABIN670148

The Rabbit Polyclonal anti-CCR2 antibody has been validated for IHC (p). It is suitable to detect CCR2 in samples from Human, Mouse, Rat and Dog.

Quick Overview for CCR2 antibody (Biotin) (ABIN670148)

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR2 antibody is conjugated to Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CCR2 Antibody (Biotin)

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CCR-2

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CCR2

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Alternative Name: CCR-2

Background:

Synonyms: C-C Chemokine receptor 2B, C C chemokine receptor type 2, C C CKR 2, CC chemokine receptor type 2, CC CKR 2, CCCKR2, CCR 2, CCR1L, CCR2A, CCR2B, CCR5L, CD192, CD192 antigen, Chemokine C C mot receptor 2, Chemokine CC Mot Receptor 2, CKR 2, CKR2, CKR2A, CKR2B, CMKBR2, MCP 1 R, MCP1 RECEPTOR, MCP1R, Monocyte chemoattractant protein 1 receptor, Monocyte Chemotactic Protein 1 Receptor, CCR2_HUMAN, C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CCR-2, CCR2, Monocyte chemoattractant protein 1 receptor, MCP-1-R.

Background: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009].

Molecular Weight: 41kDa

Gene ID: 1231

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process