CCR2 antibody (Cy5)

Catalog No. ABIN670150

This Rabbit Polyclonal antibody specifically detects CCR2 in IF (p). It exhibits reactivity toward Human, Mouse, Rat and Dog.

Quick Overview for CCR2 antibody (Cy5) (ABIN670150)

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR2 antibody is conjugated to Cy5

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CCR2 Antibody (Cy5)

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CCR-2

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCR2

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Alternative Name: CCR-2

Background:

Synonyms: C-C Chemokine receptor 2B, C C chemokine receptor type 2, C C CKR 2, CC chemokine receptor type 2, CC CKR 2, CCCKR2, CCR 2, CCR1L, CCR2A, CCR2B, CCR5L, CD192, CD192 antigen, Chemokine C C mot receptor 2, Chemokine CC Mot Receptor 2, CKR 2, CKR2, CKR2A, CKR2B, CMKBR2, MCP 1 R, MCP1 RECEPTOR, MCP1R, Monocyte chemoattractant protein 1 receptor, Monocyte Chemotactic Protein 1 Receptor, CCR2_HUMAN, C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CCR-2, CCR2, Monocyte chemoattractant protein 1 receptor, MCP-1-R.

Background: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009].

Molecular Weight: 41kDa

Gene ID: 1231

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process