Endoglin antibody (AA 601-658) (Biotin)

Catalog No. ABIN670403

The Rabbit Polyclonal anti-Endoglin antibody has been validated for ELISA and IHC (p). It is suitable to detect Endoglin in samples from Human and Rat.

Quick Overview for Endoglin antibody (AA 601-658) (Biotin) (ABIN670403)

Target: Endoglin (ENG)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endoglin antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Endoglin Antibody (Biotin)

Binding Specificity: AA 601-658

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD105

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105

Background:

Synonyms: END, HHT1, ORW1, Endoglin, CD15, ENG

Background: Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

Gene ID: 2022

UniProt: P17813