PTGS1 antibody (AA 151-250) (Biotin)

Catalog No. ABIN670448

The Rabbit Polyclonal anti-PTGS1 antibody is suitable to detect PTGS1 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC (p) and IHC (fro).

Quick Overview for PTGS1 antibody (AA 151-250) (Biotin) (ABIN670448)

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGS1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PTGS1 Antibody (Biotin)

Binding Specificity: AA 151-250

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat Cyclooxygenase 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PTGS1

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Alternative Name: Cyclooxygenase 1

Background:

Synonyms: Cyclooxygenase-1, Cyclooxygenase 1, COX-1, COX 1, COX1, Cyclooxygenase1, Prostaglandin-endoperoxide synthase-1, prostaglandin-endoperoxide synthase 1, PTGS-1, Prostaglandin G/H synthase 1 precursor, prostaglandin G/H synthase 1 isoform 1 precursor, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1, PGH1_HUMAN, PTGS1, Prostaglandin G/H synthase 1 precursor.

Background: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012].

UniProt: Q63921