Growth Hormone Receptor antibody (GHR) (AA 290-340)

Details for Product anti-GHR Antibody No. ABIN671481, Supplier: Log in to see
Antigen
  • GHBP
  • AA986417
  • GHR/BP
  • GHR
  • ghr
  • growth hormone receptor
  • growth hormone receptor L homeolog
  • GHR
  • Ghr
  • ghr.L
  • ghr
Alternatives
anti-Human Growth Hormone Receptor antibody for Immunohistochemistry (Frozen Sections)
Epitope
AA 290-340
14
9
5
4
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
67
38
36
16
2
2
1
1
1
1
Host
Rabbit
69
16
2
Clonality
Polyclonal
Conjugate
This Growth Hormone Receptor antibody is un-conjugated
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
53
30
13
13
12
11
5
3
3
2
2
2
1
1
1
Options
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Immunogen KLH conjugated synthetic peptide derived from human GHR
Isotype IgG
Purification Purified by Protein A.
Alternative Name GHR (GHR Antibody Abstract)
Background

Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.

Subcellular location: Cytoplasm

Synonyms: GHBP, Growth hormone receptor, GH receptor, Somatotropin receptor, GHR

Gene ID 2690
UniProt P10912
Pathways NF-kappaB Signaling, JAK-STAT Signaling, Response to Growth Hormone Stimulus
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
Supplier Images
Immunohistochemistry (IHC) image for anti-Growth Hormone Receptor (GHR) (AA 290-340) antibody (ABIN671481) Formalin-fixed and paraffin embedded rat liver tissue labeled Anti-GHR Polyclonal Ant...
Flow Cytometry (FACS) image for anti-Growth Hormone Receptor (GHR) (AA 290-340) antibody (ABIN671481) Human A549 cell lysates probed with Rabbit Anti-GHR Polyclonal Antibody, Unconjugated .
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Growth Hormone Receptor (GHR) (AA 290-340) antibody (ABIN671481) This image was generously provided by Brandon Menzies, PhD, from The University of Me...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Growth Hormone Receptor (GHR) (AA 290-340) antibody (ABIN671481) Formalin-fixed and paraffin embedded rat liver tissue labeled Anti-GHR Polyclonal Ant...
Product cited in: Zhao, Feng, Zhang, Kou, Li, Liu, Zhang, Cui, Chu, Shen, Min: "Inhibition of peripubertal sheep mammary gland development by cysteamine through reducing progesterone and growth factor production." in: Theriogenology, Vol. 89, pp. 280-288, 2017 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Sheep (Ovine)).

Chu, Zhao, Feng, Zhang, Liu, Cheng, Li, Shen, Cao, Li, Min: "MicroRNA-126 participates in lipid metabolism in mammary epithelial cells." in: Molecular and cellular endocrinology, Vol. 454, pp. 77-86, 2017 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Human).

Hetz, Menzies, Shaw, Rao, Clarke, Renfree: "Growth axis maturation is linked to nutrition, growth and developmental rate." in: Molecular and cellular endocrinology, Vol. 411, pp. 38-48, 2015 (PubMed).

Song, Yang, Tang, Chen: "Effects of sericin on the testicular growth hormone/insulin-like growth factor-1 axis in a rat model of type 2 diabetes." in: International journal of clinical and experimental medicine, Vol. 8, Issue 7, pp. 10411-9, 2015 (PubMed).

Yang, Sun, Sun, Qi: "Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte." in: Molecular biology reports, Vol. 39, Issue 9, pp. 9113-22, 2012 (PubMed).

Wang, Zhou, Lin, Wang, Lin, Li: "RhGH attenuates ischemia injury of intrahepatic bile ducts relating to liver transplantation." in: The Journal of surgical research, Vol. 171, Issue 1, pp. 300-10, 2011 (PubMed).

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