Fibronectin antibody (AA 1201-1300) (FITC)

Catalog No. ABIN671653

This Rabbit Polyclonal antibody specifically detects Fibronectin in WB, IF (p) and IF (cc). It exhibits reactivity toward Human, Rat, Mouse and Cowand has been mentioned in 1 publication.

Quick Overview for Fibronectin antibody (AA 1201-1300) (FITC) (ABIN671653)

Target: Fibronectin

Reactivity: Human, Rat, Mouse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibronectin antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-Fibronectin Antibody (FITC)

Binding Specificity: AA 1201-1300

Cross-Reactivity: Cow, Human, Mouse, Rat

Predicted Reactivity: Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Fibronectin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-Fibronectin antibody (FITC) (ABIN671653)

Kang, Baik, Yoo, Kim, Cheong, Park, Kang, Ha: "Aliskiren Regulates Neonatal Fc Receptor and IgG Metabolism with Attenuation of Anti-GBM Glomerulonephritis in Mice." in: Nephron, Vol. 134, Issue 4, pp. 272-282, (2016) (PubMed).

Target Details for Fibronectin

Target: Fibronectin

Background:

Synonyms: Fn, Fn-1, E3327I9, Fibronectin, Fn1

Background: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling (By similarity).

Gene ID: 14268

UniProt: P11276