PON1 antibody (AA 30-274)

Catalog No. ABIN7354529

The Rabbit Polyclonal anti-PON1 antibody has been validated for ELISA (Detection). It is suitable to detect PON1 in samples from Mouse.

Quick Overview for PON1 antibody (AA 30-274) (ABIN7354529)

Target: PON1 (Paraoxonase 1 (PON1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON1 antibody is un-conjugated

Application: ELISA (Detection)

Product Details anti-PON1 Antibody

Binding Specificity: AA 30-274

Purpose: Rabbit IgG polyclonal antibody for PON1 detection. Tested with ELISA(Det) in Mouse.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for PON1 detection. Tested with ELISA(Det) in Mouse.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse PON1 recombinant protein (Position: A30-D274).

Isotype: IgG

Application Details

Application Notes:

Application details: ELISA(Det)|0.1-0.5 μg/mL

Comment:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for PON1

Target: PON1 (Paraoxonase 1 (PON1))

Alternative Name: Pon1

Background:

Synonyms: Serum paraoxonase/arylesterase 1, PON 1

Background: Serum paraoxonase/arylesterase 1 (PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-γ, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.

Gene ID: 18979

UniProt: P52430