RP2 antibody (AA 244-348)

Catalog No. ABIN6719513

Product Details anti-RP2 Antibody

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Binding Specificity: AA 244-348

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for RP2 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for RP2 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human RP2 recombinant protein (Position: D244-M348).

Isotype: IgG

Application Details

Application Notes:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

Comment:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for RP2

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Alternative Name: RP2 (RP2 Products)

Synonyms: Rp2h antibody, RGD1565124 antibody, RP2 antibody, wu:fj10e02 antibody, wu:fm72d05 antibody, zfrp2 antibody, zgc:55632 antibody, DELXp11.3 antibody, NM23-H10 antibody, NME10 antibody, TBCCD2 antibody, XRP2 antibody, AI662636 antibody, Rp2 antibody, RP2, ARL3 GTPase activating protein antibody, XRP2 protein antibody, XRP2-like protein antibody, retinitis pigmentosa 2 (X-linked recessive) antibody, RP2, ARL3 GTPase activating protein S homeolog antibody, retinitis pigmentosa 2 homolog antibody, Rp2 antibody, RP2 antibody, Bm1_36735 antibody, PITG_13367 antibody, LOAG_11813 antibody, rp2 antibody, rp2.S antibody

Background:

Synonyms: Protein XRP2, RP2

Background: Protein XRP2 is a protein that in humans is encoded by the RP2 gene. It is mapped to Xp11.3. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death. The RP2 protein is also involved in regulating the function and extension of outer segment of cone photoreceptors in mice.

Gene ID: 6102

UniProt: O75695

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process