RP2 antibody

Catalog No. ABIN7469581

The Rabbit Polyclonal anti-RP2 antibody is suitable to detect RP2 in samples from Human. It has been validated for WB.

Quick Overview for RP2 antibody (ABIN7469581)

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RP2 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human RP2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.77 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RP2

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Alternative Name: RP2

Background:

Synonyms: RP2 activator of ARL3 GTPase , DELXp11.3 , NM23-H10 , NME10 , TBCCD2 , XRP2

Background: The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death [provided by RefSeq]

Molecular Weight: 40 kDa

Gene ID: 6102

UniProt: O75695

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process