MME antibody (Alexa Fluor 647)

Catalog No. ABIN6721860

The Alexa Fluor 647-conjugated Mouse Monoclonal anti-MME antibody (Clone CB-CALLA) (ABIN6721860) specifically detects MME in FACS. The antibody is reactive with Human samples.

Quick Overview for MME antibody (Alexa Fluor 647) (ABIN6721860)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MME antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS)

Clone: CB-CALLA

Product Details anti-MME Antibody (Alexa Fluor 647)

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Alternative Name: CD10

Target Type: Chemical

Background:

Synonyms: Neprilysin,MME,CALLA,NEP,Neutral endopeptidase,SFE,CD10

Background: CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.

Gene ID: 4311

UniProt: P08473

Pathways: RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration