CD45 antibody (PE-Cy7)
Quick Overview for CD45 antibody (PE-Cy7) (ABIN6727496)
Target
See all CD45 (PTPRC) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Isotype
- IgG2b, kappa
-
-
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC Reactivity: Human, Dog FACS, IHC, WB, StM Host: Mouse Monoclonal 2B11-PD7-26 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibodyPTPRC Reactivity: Human FACS, WB, IP, IHC (p), ICC Host: Mouse Monoclonal MEM-28 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 193-575) antibodyPTPRC Reactivity: Human IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 371-556) antibodyPTPRC Reactivity: Mouse IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 24-575) antibodyPTPRC Reactivity: Human FACS, IHC, WB, IF, ELISA Host: Mouse Monoclonal 17H9D4 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 378-577) antibodyPTPRC Reactivity: Human, Mouse, Rat FACS, IHC, WB, ELISA, ICC Host: Mouse Monoclonal 2H3E2 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 431-577) antibodyPTPRC Reactivity: Human FACS, IHC, ELISA Host: Mouse Monoclonal 1B9B10 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 928-989) antibodyPTPRC Reactivity: Human IHC, ELISA Host: Mouse Monoclonal 5D3A3 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (C-Term) antibodyPTPRC Reactivity: Human, Mouse, Rat, Dog, Chicken, Cow, Cat, Rabbit, Sheep, Guinea Pig, Pig, Goat, Horse, Monkey, Hamster, Donkey, Avian WB, IHC (p), IHC (f) Host: Goat Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibodyPTPRC Reactivity: Human FACS, IHC, WB, IF, StM Host: Rabbit Monoclonal PTPRC-2877R unconjugated Recombinant Antibody
-
-
Application Notes
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
-
Comment
-
Matching Isotype Control: PE/Cyanine7 Rat IgG2b, κ Isotype Control (ABIN7469863)
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.2 mg/mL
-
Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
-
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C
-
Storage Comment
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
-
-
- CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
-
Alternative Name
- CD45
-
Background
- Receptor-type tyrosine-protein phosphatase C,Ptprc,L-CA,Ly-5,T200,CD45,CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
-
Gene ID
- 19264
-
UniProt
- P06800
-
Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
Target
-
