CD14 antibody (PE-Cy7)

Catalog No. ABIN6728105

This Rat Monoclonal antibody specifically detects CD14 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for CD14 antibody (PE-Cy7) (ABIN6728105)

Target: CD14

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD14 antibody is conjugated to PE-Cy7

Application: Flow Cytometry (FACS)

Clone: Sa14-2

Product Details anti-CD14 Antibody (PE-Cy7)

Isotype: IgG2a, kappa

Application Details

Application Notes: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Comment:

Matching Isotype Control: PE/Cyanine7 Rat IgG2a, κ Isotype Control (ABIN7469844)

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD14

Target: CD14

Alternative Name: CD14

Background: CD 14,Myeloid cell-specific leucine-rich glycoprotein,Monocyte differentiation antigen CD14,CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.

Gene ID: 12475

UniProt: P10810

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades