CD14 antibody (Alexa Fluor 488)

Catalog No. ABIN6728114

The Rat Monoclonal anti-CD14 antibody is suitable to detect CD14 in samples from Mouse. It has been validated for FACS.

Quick Overview for CD14 antibody (Alexa Fluor 488) (ABIN6728114)

Target: CD14

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD14 antibody is conjugated to Alexa Fluor 488

Application: Flow Cytometry (FACS)

Clone: Sa14-2

Product Details anti-CD14 Antibody (Alexa Fluor 488)

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD14

Target: CD14

Alternative Name: CD14

Background:

Synonyms: CD 14,Myeloid cell-specific leucine-rich glycoprotein,Monocyte differentiation antigen CD14

Background: CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.

Gene ID: 12475

UniProt: P10810

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades