IL12A antibody (AA 51-150)

Catalog No. ABIN672951

Cited in 2+ publications. The Rabbit Polyclonal anti-IL12A antibody (ABIN672951) specifically detects IL12A in WB, ELISA, IHC (p), FACS, IHC (fro), IF (p) and IF (cc). The antibody is reactive with Mouse and Rat samples.

Quick Overview for IL12A antibody (AA 51-150) (ABIN672951)

Target: IL12A (Interleukin 12 alpha (IL12A))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL12A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-IL12A Antibody

Binding Specificity: AA 51-150

Cross-Reactivity: Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse IL-12 alpha

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-IL12A antibody (ABIN672951)

Yang, Liu, Zhang, Hu, Chen, Wang, Yin, Li, Qi: "Effect of IL-17 in the development of colon cancer in mice." in: Oncology letters, Vol. 12, Issue 6, pp. 4929-4936, (2017) (PubMed).

Taylor-Fishwick, Weaver, Grzesik, Chakrabarti, Green-Mitchell, Imai, Kuhn, Nadler: "Production and function of IL-12 in islets and beta cells." in: Diabetologia, Vol. 56, Issue 1, pp. 126-35, (2012) (PubMed).

Target Details for IL12A

Target: IL12A (Interleukin 12 alpha (IL12A))

Alternative Name: IL-12 alpha

Background:

Synonyms: p35, Ll12a, Il-12a, IL-12p35, Interleukin-12 subunit alpha, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35, Il12a

Background: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.

Gene ID: 16159

UniProt: P43431

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation