Tuberin antibody

Catalog No. ABIN6735149

This Mouse Monoclonal antibody specifically detects Tuberin in ELISA, WB and IP. It exhibits reactivity toward Human.

Quick Overview for Tuberin antibody (ABIN6735149)

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tuberin antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Tuberin Antibody

Specificity: Recognizes human tuberin encoded on tuberous sclerosis-2 (TSC2) gene with approximately 200kD. It does not cross-react with hamartin encoded on tuberous sclerosis-1 (TSC1) gene. Reactivity is confirmed with tuberin and hamartin overexpressed cell lysates.

Purification: Protein A Column

Immunogen: Recombinant human tuberin protein.

Isotype: IgG1

Application Details

Application Notes: ELISA, IP (5 - 10 µg/mL), WB (1 - 3 µg/mL)

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: PBS, pH 7.4, 0.1% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Long term: Add glycerol (40-50%) -20°C, Short term: +4°C

Target Details for Tuberin

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Alternative Name: Tuberin / TSC2

Background: Standard Gene Symbol: TSC2, Synonyms: TSC2, LAM, Tuberous sclerosis 2 protein, TSC4, Tuberin, Tuberous sclerosis 2

Gene ID: 7249

UniProt: P49815

Pathways: RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus