BIM antibody (pSer65)

Catalog No. ABIN6735183

This Rabbit Polyclonal antibody specifically detects BIM in WB. It exhibits reactivity toward Rat.

Quick Overview for BIM antibody (pSer65) (ABIN6735183)

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BIM Antibody

Binding Specificity: pSer65

Specificity: Recognizes rat BimEL. This antibody is observed to react with human BimEL when phosphorylated at serine 69. Mouse BimEL (100% homologous) has not been tested, but is expected to react.

Cross-Reactivity: Human

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic phosphopeptide derived from the region of rat BimEL that contains serine 65 (serine 69 in the human sequence). The sequence is conserved in human and mouse.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS (without Mg2+, Ca2+), 1 mg/mL BSA (IgG, protease free), pH 7.2, 0.1% sodium azide, 50% glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.

Target Details for BIM

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Alternative Name: BCL2L11 / BIM

Background: Standard Gene Symbol: BCL2L11, Gene Family: Apoptosis, Synonyms: BCL2L11, BIM-alpha6, BIM-beta7, Bcl-2-like protein 11, BIM-beta6, BimL, BimS, Bcl-2 interacting protein Bim, BimEL, BAM, Bcl2-L-11, BIM, BOD

Gene ID: 10018

UniProt: O43521

Pathways: PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity