Presenilin 1 antibody (Val293)

Catalog No. ABIN6735742

This anti-Presenilin 1 antibody is a Rabbit Polyclonal antibody detecting Presenilin 1 in WB, ELISA and IP. Suitable for Human.

Quick Overview for Presenilin 1 antibody (Val293) (ABIN6735742)

Target: Presenilin 1 (PSEN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Presenilin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-Presenilin 1 Antibody

Binding Specificity: Val293

Specificity: Detects endogenous levels of the carboxy-terminal fragment of presenilin 1 (~22kD). The antibody detects the full length protein (55kD) to a lesser extent. Species cross-reactivity: Human, rat and monkey. Species sequence homology: mouse 100 % .

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide (KLH coupled) corresponding to residues around valine 293 of human presenilin 1.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA, IP (1:100), WB (1:500)

Usage: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Western Blot: 1:500. Immunoprecipitation: 1:100.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Presenilin 1

Target: Presenilin 1 (PSEN1)

Alternative Name: PSEN1 / Presenilin 1

Background: Name/Gene ID: PSEN1
Subfamily: Aspartic A22A
Family: protease

Synonyms: PSEN1, AD3, Alzheimer disease 3, FAD, Protein S182, PS1, S182, PS-1, PSNL1, Presenilin 1, Presenilin-1

Gene ID: 5663

UniProt: P49768

Pathways: Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport