PRKACA antibody (AA 8-22)

Catalog No. ABIN6735745

The Rabbit Polyclonal anti-PRKACA antibody (ABIN6735745) specifically detects PRKACA in WB. The antibody is reactive with Human samples.

Quick Overview for PRKACA antibody (AA 8-22) (ABIN6735745)

Target: PRKACA (Protein Kinase A, alpha (PRKACA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKACA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRKACA Antibody

Binding Specificity: AA 8-22

Specificity: Recognizes PKA purified from bovine heart and recombinant human alpha isoform of PKA expressed in CHO cells. Species cross-reactivity: mouse, rat, hamster, bovine and porcine. Cross-reactivity with the beta-isoform of mammalian PKA is possible since it shares identity in 14 of 15 residues.

Cross-Reactivity: Hamster, Cow (Bovine), Mammalian, Mouse (Murine), Pig (Porcine), Rat (Rattus)

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Monkey, Mouse, Rat, Sheep, Hamster, Elephant, Bovine, Dog, Pig (100%) Orangutan, Gibbon, Marmoset, Stickleback (93%) Xenopus, Catfish, Salmon, Pufferfish, Zebrafish (87%).

Purification: Protein A Column

Immunogen: 16 residue synthetic peptide (KKGSEQESVKEFLAK-C) based upon amino acids 8-22 of the human 41kD alpha isoform of the catalytic subunit of PKA. The immunizing sequence is identical in mouse, rat, hamster, bovine and porcine.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.07 M Tris-glycine, pH 7.4, 0.105 M sodium chloride, 0.035% sodium azide, 30% glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for PRKACA

Target: PRKACA (Protein Kinase A, alpha (PRKACA))

Alternative Name: PRKACA

Background: Standard Gene Symbol: PRKACA, Gene Family: Protein Kinase, Gene Subfamily: cAMP, Synonyms: PRKACA, PKA C-alpha, Pka calpha, PKACA

Gene ID: 5566

UniProt: P17612

Pathways: NF-kappaB Signaling, Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, Lipid Metabolism, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection