IRS1 antibody (Ser639)

Catalog No. ABIN6740191

The Rabbit Polyclonal anti-IRS1 antibody is suitable to detect IRS1 in samples from Human. It has been validated for WB.

Quick Overview for IRS1 antibody (Ser639) (ABIN6740191)

Target: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IRS1 Antibody

Binding Specificity: Ser639

Specificity: Recognizes endogenous levels of total IRS-1 protein.

Purification: Immunoaffinity Chromatography

Immunogen: Synthesized non-phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 639 (P-K-SP-V-S).

Isotype: IgG

Application Details

Application Notes: WB (1:500 - 1:1000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.

Target Details for IRS1

Target: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Alternative Name: IRS1 / IRS-1

Background: Standard Gene Symbol: IRS1, Synonyms: IRS1, IRS-1, HIRS-1, Insulin receptor substrate 1

Gene ID: 3667

UniProt: P35568

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process