FGFR2 antibody (AA 292-341)

Catalog No. ABIN6746747

This anti-FGFR2 antibody is a Rabbit Polyclonal antibody detecting FGFR2 in WB. Suitable for Human, Mouse, Rat, Monkey, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep and Pig. This Primary Antibody has been cited in 2+ publications.

Quick Overview for FGFR2 antibody (AA 292-341) (ABIN6746747)

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Reactivity: Human, Mouse, Rat, Monkey, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGFR2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FGFR2 Antibody

Binding Specificity: AA 292-341

Specificity: Human FGFR2

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat, Sheep, Dog, Bovine, Rabbit, Horse, Pig, Guinea pig (100%) Chicken (92%) Zebrafish (90%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa292-341 of human FGFR2 (P21802, NP_075259). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Mouse, Rat, Sheep, Elephant, Dog, Bovine, Rabbit, Horse, Pig, Guinea pig, Zebra finch (100%), Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus (92%), Zebrafish (90%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-FGFR2 antibody (ABIN6746747)

Steegmaier, Yang, Yoo, Huang, Shen, Yu, Luo, Scheller: "Three novel proteins of the syntaxin/SNAP-25 family." in: The Journal of biological chemistry, Vol. 273, Issue 51, pp. 34171-9, (1999) (PubMed).

Thoreau, Bergès, Callebaut, Guillier-Gencik, Gressin, Bernheim, Karst, Mornon, Kitzis, Chomel: "Molecular cloning, expression analysis, and chromosomal localization of human syntaxin 8 (STX8)." in: Biochemical and biophysical research communications, Vol. 257, Issue 2, pp. 577-83, (1999) (PubMed).

Target Details for FGFR2

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Alternative Name: FGF Receptor / FGFR2

Background: Name/Gene ID: FGFR2
Subfamily: FGF Receptor
Family: Protein Kinase

Synonyms: FGFR2, BEK, BBDS, Bacteria-expressed kinase, CD332 antigen, CFD1, Craniofacial dysostosis 1, CEK3, Fgf bek, FGF receptor, Hydroxyaryl-protein kinase, Jackson-Weiss syndrome, JWS, FGF Receptor 2, KSAM, KGFR, Soluble FGFR4 variant 4, BFR-1, TK14, TK25, CD332, ECT1, K-SAM

Gene ID: 2263

NCBI Accession: NP_075259

UniProt: P21802

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding