IFIH1 antibody (AA 612-661)

Catalog No. ABIN6747017

Product Details anti-IFIH1 Antibody

Target: IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

Binding Specificity: AA 612-661

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFIH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human IFIH1 / MDA5

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Bovine, Horse (84%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa612-661 of human IFIH1 (Q9BYX4, NP_071451). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey (100%), Marmoset, Elephant (92%), Bovine, Horse (84%), Panda (83%), Mouse (76%), Rat (75%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for IFIH1

Target: IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

Alternative Name: IFIH1 / MDA5 (IFIH1 Products)

Synonyms: MDA5 antibody, Hlcd antibody, IDDM19 antibody, MDA-5 antibody, RLR-2 antibody, 9130009C22Rik antibody, Helicard antibody, RGD1560496 antibody, interferon induced with helicase C domain 1 antibody, IFIH1 antibody, Ifih1 antibody

Background: Name/Gene ID: IFIH1
Family: DEAD box protein

Synonyms: IFIH1, Helicase with 2 CARD domains, MDA-5, MDA5, Helicard, IDDM19, RLR-2, RH116, CADM-140 autoantigen, Hlcd, RIG-I-like receptor 2

Gene ID: 64135

NCBI Accession: NP_071451

UniProt: Q9BYX4

Pathways: Activation of Innate immune Response