IFIH1 antibody

Catalog No. ABIN7267950

The Rabbit Monoclonal anti-IFIH1 antibody (ABIN7267950) specifically detects IFIH1 in WB. The antibody is reactive with Human samples.

Quick Overview for IFIH1 antibody (ABIN7267950)

Target: IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IFIH1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IFIH1 Antibody

Purpose: MDA5 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human MDA5

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IFIH1

Target: IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

Alternative Name: IFIH1

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012],AGS7, Hlcd, IDDM19, MDA-5, MDA5, RLR-2, SGMRT1,Apoptosis,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Cytokines,Cytokines_Interferons,Epigenetics & Nuclear Signaling,Immunology & Inflammation,IFIH1

Molecular Weight: 117kDa

Gene ID: 64135

UniProt: Q9BYX4

Pathways: Activation of Innate immune Response