Vitronectin antibody (AA 381-478)

Catalog No. ABIN675518

There is 1 publication for this product available. The Rabbit Polyclonal anti-Vitronectin antibody is suitable to detect Vitronectin in samples from Mouse and Rat. It has been validated for ELISA, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for Vitronectin antibody (AA 381-478) (ABIN675518)

Target: Vitronectin (VTN)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vitronectin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Vitronectin Antibody

Binding Specificity: AA 381-478

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Vitronectin

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Vitronectin antibody (ABIN675518)

Wang, Jiang, Peng, Guo, Shang, Chen, Wu, Chen: "Induced apoptosis of osteoblasts proliferating on polyhydroxyalkanoates." in: Biomaterials, Vol. 34, Issue 15, pp. 3737-46, (2013) (PubMed).

Target Details for Vitronectin

Target: Vitronectin (VTN)

Alternative Name: Vitronectin

Background:

Synonyms: VN, V75, VNT, Vitronectin, S-protein, Serum-spreading factor, VTN

Background: Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.

Gene ID: 7448

UniProt: P04004

Pathways: Autophagy, Smooth Muscle Cell Migration