Vitronectin antibody (AA 381-478) (HRP)

Catalog No. ABIN675527

The Rabbit Polyclonal anti-Vitronectin antibody is suitable to detect Vitronectin in samples from Human. It has been validated for IHC (p) and IHC (fro).

Quick Overview for Vitronectin antibody (AA 381-478) (HRP) (ABIN675527)

Target: Vitronectin (VTN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vitronectin antibody is conjugated to HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Vitronectin Antibody (HRP)

Binding Specificity: AA 381-478

Purpose: Vitronectin Polyclonal Antibody, HRP Conjugated

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Vitronectin

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Vitronectin

Target: Vitronectin (VTN)

Alternative Name: Vitronectin

Background:

Synonyms: VN, V75, VNT, Vitronectin, S-protein, Serum-spreading factor, VTN

Background: Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.

Gene ID: 7448

UniProt: P04004

Pathways: Autophagy, Smooth Muscle Cell Migration