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Tyrosine Hydroxylase antibody (AA 1-20)

The Mouse Monoclonal anti-Tyrosine Hydroxylase antibody has been validated for WB and IP. It is suitable to detect Tyrosine Hydroxylase in samples from Human, Rat, Mouse, Cow, Rabbit, Monkey and Guinea Pig.
Catalog No. ABIN6757239

Quick Overview for Tyrosine Hydroxylase antibody (AA 1-20) (ABIN6757239)

Target

See all Tyrosine Hydroxylase (TH) Antibodies
Tyrosine Hydroxylase (TH)

Reactivity

  • 123
  • 120
  • 98
  • 10
  • 9
  • 8
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
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  • 1
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  • 1
  • 1
  • 1
Human, Rat, Mouse, Cow, Rabbit, Monkey, Guinea Pig

Host

  • 121
  • 36
  • 7
  • 6
  • 2
Mouse

Clonality

  • 125
  • 45
  • 1
Monoclonal

Conjugate

  • 120
  • 8
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Tyrosine Hydroxylase antibody is un-conjugated

Application

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  • 17
  • 14
  • 13
  • 6
  • 4
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  • 2
  • 1
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  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • Binding Specificity

    • 20
    • 15
    • 14
    • 12
    • 12
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 1-20

    Specificity

    Recognizes intact and the N-terminal (1-20aa) region of TH. Species cross-reactivity: Rat, mouse, human, bovine, monkey, sheep, guinea pig and rabbit. The monoclonal antibody has broad species cross-reactivity.

    Purification

    Immunoaffinity purified

    Immunogen

    Purified rat tyrosine hydroxylase (TH).

    Isotype

    IgG1
  • Application Notes

    Approved: IP, WB (1:1000 - 1:5000)

    Usage: Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 1:1000-1:5000 using Chemiluminescence substrates. Immunoprecipitation (Native and denatured TH): 10-20 μL antibody per 100-200 μg of protein extracts.

    Comment

    Target Species of Antibody: Rat

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    0.02 % sodium merthiolate or 0.1 % sodium azide as preservative, 40 % glycerol.

    Preservative

    Sodium azide, Thimerosal (Merthiolate)

    Precaution of Use

    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handling Advice

    Avoid repeat freeze-thaw cycles.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target

    Tyrosine Hydroxylase (TH)

    Alternative Name

    TH / Tyrosine Hydroxylase

    Background

    Name/Gene ID: TH
    Family: Monooxygenase

    Synonyms: TH, DYT14, Dystonia 14, TYH, Tyrosine 3-hydroxylase, Tyrosine hydroxylase, DYT5b, Tyrosine 3-monooxygenase

    Gene ID

    7054

    UniProt

    P07101

    Pathways

    Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
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