APP antibody (Thr668, Thr743)
Quick Overview for APP antibody (Thr668, Thr743) (ABIN6796338)
Target
See all APP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Thr668, Thr743
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Specificity
- Recognizes human APP when phosphorylated at Thr743/668. Species cross-Reactivity: mouse.
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Purification
- Immunoaffinity purified
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Immunogen
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Synthetic phosphopeptide corresponding to human beta Amyloid A4 around the phosphorylation site of threonine 743 (A-V-TP-P-E).
Type of Immunogen: Synthetic phospho-peptide -
Isotype
- IgG
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Application Notes
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Approved: ELISA (1:4000), IHC (1:50 - 1:100), WB (1:500 - 1:1000)
Usage: Suitable for use in ELISA, Western Blot and Immunohistochemistry. ELISA:1:4000. Western Blot:1:500-1:1000. Immunohistochemistry:1:50-1:100. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Aliquot to Avoid repeated freezing and thawing.
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Storage
- 4 °C,-20 °C
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Storage Comment
- May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.
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- APP (Amyloid beta (A4) Precursor Protein (APP))
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Alternative Name
- APP / beta Amyloid
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Background
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Name/Gene ID: APP
Family: Amyloid precursor protein
Synonyms: APP, ABPP, A4, ABETA, AD1, Alzheimer disease, Amyloid beta, Beta-amyloid peptide, APPI, Beta amyloid, CVAP, AAA, PN2, PreA4, Amyloid beta A4 protein, Peptidase nexin-II, CTFgamma, PN-II, Protease nexin-II -
Gene ID
- 351
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UniProt
- P05067
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Pathways
- Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
Target
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