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ITK antibody (AA 101-200)

This Rabbit Polyclonal antibody specifically detects ITK in ELISA, IF (cc), IF (p), IHC (p), IHC (fro). It exhibits reactivity toward Human.
Catalog No. ABIN680653

Quick Overview for ITK antibody (AA 101-200) (ABIN680653)

Target

See all ITK Antibodies
ITK (IL2-Inducible T-Cell Kinase (ITK))

Reactivity

  • 49
  • 22
  • 12
  • 6
  • 3
Human

Host

  • 64
  • 5
  • 2
Rabbit

Clonality

  • 63
  • 8
Polyclonal

Conjugate

  • 35
  • 8
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ITK antibody is un-conjugated

Application

  • 43
  • 34
  • 17
  • 13
  • 13
  • 9
  • 6
  • 4
  • 3
  • 3
  • 3
  • 1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Binding Specificity

    • 10
    • 10
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200

    Predicted Reactivity

    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human ITK/PSCTK2

    Isotype

    IgG
  • Application Notes

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Expiry Date

    12 months
  • Target

    ITK (IL2-Inducible T-Cell Kinase (ITK))

    Alternative Name

    ITK

    Background

    Synonyms: EMT, Homolog of mouse T cell itk/tsk, IL2 inducible T cell kinase, Kinase EMT, LYK, MGC126257, MGC126258, PSCTK 2, PSCTK2, T cell specic kinase, TSK, Tyrosine protein kinase, Tyrosine protein kinase ITK/TSK, Tyrosine protein kinase Lyk.

    Background: ITK is a T cell signaling protein. The Tec family of non receptor tyrosine kinases is composed of six proteins designated Tec, ITK (also known as Emt or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain pleckstrin homology (PH) and Tec homology (TH) domains in their amino termini. ITK associates with CD28 and becomes activated subsequent to CD28 ligation.

    Gene ID

    3702

    Pathways

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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