C3AR1 antibody (AA 401-482)

Catalog No. ABIN682213

This Rabbit Polyclonal antibody specifically detects C3AR1 in WB, ELISA, IHC (fro), IF (cc), IF (p) and IHC (p). It exhibits reactivity toward Human and Mouse and has been mentioned in 2+ publications.

Quick Overview for C3AR1 antibody (AA 401-482) (ABIN682213)

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C3AR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C3AR1 Antibody

Binding Specificity: AA 401-482

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C3a Receptor/C3aR

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-C3AR1 antibody (ABIN682213)

Schäfer, Rasras, Ormenisan, Amslinger, Enzmann, Jägle, Pauly: "Complement Factor H-Related 3 Enhanced Inflammation and Complement Activation in Human RPE Cells." in: Frontiers in immunology, Vol. 12, pp. 769242, (2022) (PubMed).

Shinjyo, de Pablo, Pekny, Pekna: "Complement Peptide C3a Promotes Astrocyte Survival in Response to Ischemic Stress." in: Molecular neurobiology, (2015) (PubMed).

Target Details for C3AR1

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Alternative Name: C3a Receptor

Background:

Synonyms: AZ3B, C3AR, HNFAG09, C3a anaphylatoxin chemotactic receptor, C3a-R, C3AR1, C3R1

Background: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

Gene ID: 719

UniProt: Q16581

Pathways: Complement System