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BMI1 antibody (AA 61-160)

BMI1 Reactivity: Human ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN682678
$352.31
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target See all BMI1 Antibodies
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    Binding Specificity
    • 16
    • 8
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 61-160
    Reactivity
    • 123
    • 52
    • 32
    • 11
    • 9
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 85
    • 37
    • 6
    Rabbit
    Clonality
    • 88
    • 40
    Polyclonal
    Conjugate
    • 83
    • 9
    • 9
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BMI1 antibody is un-conjugated
    Application
    • 103
    • 62
    • 47
    • 24
    • 15
    • 12
    • 11
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Predicted Reactivity
    Mouse,Rat,Dog,Cow,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Bmi1/PCGF4
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    Alternative Name
    BMI1 (BMI1 Products)
    Synonyms
    FLVI2/BMI1, PCGF4, RNF51, AW546694, Bmi-1, Pcgf4, bmi1, pcgf4, psc1, wu:fb17g03, wu:fd18f06, BMI-1, bmi-1, bmi1-a, bmi1-b, bmi1b, rnf51, xbmi-1, BMI1 proto-oncogene, polycomb ring finger, BMI1 polycomb ring finger oncogene, Bmi1 polycomb ring finger oncogene, bmi1 polycomb ring finger oncogene 1a, BMI1 proto-oncogene, polycomb ring finger L homeolog, BMI1, LOC100230513, Bmi1, bmi1a, bmi1.L
    Background

    Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

    Subcellular location: Cytoplasm, Nucleus

    Synonyms: PCGF4, RNF51, FLVI2/BMI1, Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51, BMI1

    Gene ID
    648
    UniProt
    P35226
    Pathways
    Cell Division Cycle, Autophagy
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