ATP1A1 antibody (pSer23)

Catalog No. ABIN683608

This Rabbit Polyclonal antibody specifically detects ATP1A1 in WB, IF (p), IF (cc) and IHC (fro). It exhibits reactivity toward Rat.

Quick Overview for ATP1A1 antibody (pSer23) (ABIN683608)

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ATP1A1 Antibody

Binding Specificity: pSer23

Purpose: Phospho-ATP1A1 (Ser23) Polyclonal Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from rat ATP1A1 around the phosphorylation site of Ser23

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ATP1A1

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Alternative Name: Atp1a1

Background:

Synonyms: alpha 1 Sodium Potassium ATPase phospho S23, ATP1A1, Na,K-ATPase alpha-1, Atpa-1, ATPase Na+/K+ transporting alpha 1 polypeptide, BC010319, EC 3.6.3.9, MGC3285, MGC38419, MGC51750, Na K ATPase alpha A catalytic polypeptide, Na K ATPase catalytic subunit alpha A protein, Na+/K+ ATPase 1, Na+/K+ ATPase alpha-1 subunit, Na+/K+ ATPase alpha 1 subunit, Na+/K+ ATPase 1, Nkaa1b, Sodium potassium ATPase alpha 1 polypeptide, Sodium pump 1, Sodium pump subunit alpha-1, Sodium/potassium transporting ATPase alpha 1 chain, Sodium/potassium-transporting ATPase subunit alpha-1.

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May2009].

Gene ID: 476

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process