MAP2 antibody (AA 1-120)

Catalog No. ABIN685567

This Rabbit Polyclonal antibody specifically detects MAP2 in WB, ELISA, IHC (p), IF (cc), IF (p), FACS and IHC (fro). It exhibits reactivity toward Human, Mouse, Rat and Pig and has been mentioned in 6+ publications.

Quick Overview for MAP2 antibody (AA 1-120) (ABIN685567)

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Reactivity: Human, Mouse, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MAP2 Antibody

Binding Specificity: AA 1-120

Cross-Reactivity: Human, Mouse, Pig, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAP2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-MAP2 antibody (ABIN685567)

Lu, Ben, Xiao, Peng, Zhang: "AMP-activated protein kinase activation in mediating phenylalanine-induced neurotoxicity in experimental models of phenylketonuria." in: Journal of inherited metabolic disease, (2018) (PubMed).

Usui, Sakurai, Kawasaki, Ohama, Yamawaki, Sato: "Establishment of a novel three-dimensional primary culture model for hippocampal neurogenesis." in: Physiological reports, Vol. 5, Issue 12, (2017) (PubMed).

Wang, Jing, Song, Xing: "Neuroprotective effects of Wnt/β-catenin signaling pathway against Aβ -induced tau protein over-phosphorylation in PC12 cells." in: Biochemical and biophysical research communications, Vol. 471, Issue 4, pp. 628-32, (2016) (PubMed).

Zuo, Wang, Li, Lin, Duan, Qi, Li, Sun, Wu: "Existence of glia mitigated ketamine-induced neurotoxicity in neuron-glia mixed cultures of neonatal rat cortex and the glia-mediated protective effect of 2-PMPA." in: Neurotoxicology, Vol. 44, pp. 218-30, (2014) (PubMed).

Gu, Huang, Shen, Gao, Ding, Wu, Guo: "Early activation of nSMase2/ceramide pathway in astrocytes is involved in ischemia-associated neuronal damage via inflammation in rat hippocampi." in: Journal of neuroinflammation, Vol. 10, pp. 109, (2013) (PubMed).

Huang, Xu, Cao, Cao, Zhang: "The expression of FOXJ1 in neurogenesis after transient focal cerebral ischemia." in: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, Vol. 40, Issue 3, pp. 403-9, (2013) (PubMed).

Target Details for MAP2

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Alternative Name: MAP2/MAP-2a.b.c

Background:

Synonyms: MAP2A, MAP2B, MAP2C, Microtubule-associated protein 2, MAP-2, MAP2

Background: The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

Gene ID: 4133

UniProt: P11137