MC1 Receptor antibody (AA 271-317)

Catalog No. ABIN686287

This Rabbit Polyclonal antibody specifically detects MC1 Receptor in ELISA, WB, IF (cc), IF (p), FACS, IHC (p) and IHC (fro). It exhibits reactivity toward Human and Mouseand has been mentioned in 1 publication.

Quick Overview for MC1 Receptor antibody (AA 271-317) (ABIN686287)

Target: MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC1 Receptor antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MC1 Receptor Antibody

Binding Specificity: AA 271-317

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse MC1R

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-MC1 Receptor antibody (ABIN686287)

Schmitz, Botte, Sotto, Borba, Bonfa, de Mello: "Increased corticotropin-releasing hormone (CRH) expression in cutaneous lupus lesions." in: Lupus, Vol. 24, Issue 8, pp. 854-61, (2015) (PubMed).

Target Details for MC1 Receptor

Target: MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))

Alternative Name: MC-1R/MC1 Receptor

Background:

Synonyms: Mshra, Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R, Mc1r

Background: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

Gene ID: 17199

UniProt: Q01727

Pathways: cAMP Metabolic Process, Feeding Behaviour