MC1 Receptor antibody (AA 271-317) (HRP)

Catalog No. ABIN686296

This Rabbit Polyclonal antibody specifically detects MC1 Receptor in ELISA, WB, IHC (p) and IHC (fro). It exhibits reactivity toward Human and Mouse.

Quick Overview for MC1 Receptor antibody (AA 271-317) (HRP) (ABIN686296)

Target: MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC1 Receptor antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MC1 Receptor Antibody (HRP)

Binding Specificity: AA 271-317

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse MC1R

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MC1 Receptor

Target: MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))

Alternative Name: MC-1R/MC1 Receptor

Background:

Synonyms: Mshra, Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R, Mc1r

Background: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

Gene ID: 17199

UniProt: Q01727

Pathways: cAMP Metabolic Process, Feeding Behaviour