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ARFIP2 antibody (AA 221-341) (Biotin)

ARFIP2 Reactivity: Human IHC (fro), IHC (p), WB Host: Rabbit Polyclonal Biotin
Catalog No. ABIN686589
$451.08
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target See all ARFIP2 Antibodies
    ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
    Binding Specificity
    • 14
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-341
    Reactivity
    • 32
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 29
    • 2
    • 1
    Rabbit
    Clonality
    • 31
    • 1
    Polyclonal
    Conjugate
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARFIP2 antibody is conjugated to Biotin
    Application
    • 16
    • 14
    • 14
    • 10
    • 4
    • 4
    • 3
    • 3
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Arfaptin 2
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C
    Expiry Date
    12 months
  • Target
    ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
    Alternative Name
    Arfaptin 2 (ARFIP2 Products)
    Synonyms
    POR1 antibody, 2310002N04Rik antibody, POR antibody, Por1 antibody, ARFIP2 antibody, im:7136059 antibody, zgc:112066 antibody, ADP ribosylation factor interacting protein 2 antibody, ADP-ribosylation factor interacting protein 2 antibody, ADP-ribosylation factor interacting protein 2b antibody, ARFIP2 antibody, Arfip2 antibody, arfip2b antibody
    Background

    ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: ARFIP2, arfaptin 2, ADP-ribosylation factor interacting protein 2, Partner of RAC1, POR1, ARFP2_HUMAN .

    Gene ID
    23647
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