JAG1 antibody

Catalog No. ABIN686677

This Rabbit Polyclonal antibody specifically detects JAG1 in WB, IHC (p), IF (cc) and IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for JAG1 antibody (ABIN686677)

Target: JAG1 (Jagged 1 (JAG1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-JAG1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Jagged1

Isotype: IgG

Application Details

Application Notes: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for JAG1

Target: JAG1 (Jagged 1 (JAG1))

Alternative Name: Jagged1

Background:

Synonyms: JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1,MGC104644, Ser 1, CD 339, CD339, CD339 antigen, Headturner, Htu, Jag 1, Jagged-1, Jagged 1, Jagged 1 Alagille syndrome, JAGL1, Ser-1, Ser1, Serrate-1, Slalom.

Background: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq].

Gene ID: 182

Pathways: Notch Signaling, Stem Cell Maintenance