AKAP8 antibody (AA 401-550) (Biotin)

Catalog No. ABIN687054

This anti-AKAP8 antibody is a Rabbit Polyclonal antibody detecting AKAP8 in ELISA, IHC (p) and IHC (fro). Suitable for Human.

Quick Overview for AKAP8 antibody (AA 401-550) (Biotin) (ABIN687054)

Target: AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP8 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-AKAP8 Antibody (Biotin)

Binding Specificity: AA 401-550

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AKAP95

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for AKAP8

Target: AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))

Alternative Name: AKAP95/AKAP8

Background:

Synonyms: AKAP8, A-kinase Anchoring Protein 95, CCK 1, CCK1, CCL 28, Chemokine C-C mot ligand 28, MEC, Mucosae associated epithelial chemokine, SCYA28, Small inducible cytokine A28, AKP8L_HUMAN.

Background: This protein belongs to the subfamily of small cytokine CC proteins. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. This cytokine displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils and binds to chemokine receptors CCR3 and CCR10. It induces calcium mobilization in a dose-dependent manner. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs.

Gene ID: 10270

Pathways: SARS-CoV-2 Protein Interactome