AKAP8 antibody (AA 401-550) (Cy5)

Catalog No. ABIN687056

The Rabbit Polyclonal anti-AKAP8 antibody has been validated for IF (cc) and IF (p). It is suitable to detect AKAP8 in samples from Human.

Quick Overview for AKAP8 antibody (AA 401-550) (Cy5) (ABIN687056)

Target: AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP8 antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-AKAP8 Antibody (Cy5)

Binding Specificity: AA 401-550

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AKAP95

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for AKAP8

Target: AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))

Alternative Name: Akap95/Akap8

Background:

Synonyms: AKAP8, A-kinase Anchoring Protein 95, CCK 1, CCK1, CCL 28, Chemokine C-C mot ligand 28, MEC, Mucosae associated epithelial chemokine, SCYA28, Small inducible cytokine A28, AKP8L_HUMAN.

Background: This protein belongs to the subfamily of small cytokine CC proteins. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. This cytokine displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils and binds to chemokine receptors CCR3 and CCR10. It induces calcium mobilization in a dose-dependent manner. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs.

Gene ID: 10270

Pathways: SARS-CoV-2 Protein Interactome