BARX1 antibody (AA 155-254)
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- Target See all BARX1 Antibodies
- BARX1 (BARX Homeobox 1 (BARX1))
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Binding Specificity
- AA 155-254
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This BARX1 antibody is un-conjugated
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Application
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificity
- BarX1 is a member of the Bar subclass of homeobox transcription factors. Studies of the Mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. Down-regulation of Barx1 promotes HCC migration, invasion and metastasis, whereas up-regulation of Barx1 inhibits HCC migration, invasion and metastasis. The loss of Barx1 expression represents a prognostic biomarker in human HCC.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment of human BARX1 protein (around aa 155-254) (exact sequence is proprietary)
- Clone
- BARX1-2759
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product BARX1 Primary Antibody
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- Application Notes
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HepG2 cell lysate. Pancreas.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- BARX1 (BARX Homeobox 1 (BARX1))
- Alternative Name
- BARX1 (BARX1 Products)
- Synonyms
- BarH4 antibody, zgc:110654 antibody, BARX1B antibody, BARX1 antibody, XBH2 antibody, barh2 antibody, barh2-a antibody, xbarhl1 antibody, BARX homeobox 1 antibody, BarH like homeobox 1 S homeolog antibody, BarH-like homeobox 1 antibody, BARX1 antibody, barx1 antibody, Barx1 antibody, barhl1.S antibody
- Background
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BarH like homeobox 1, BarX 1, BARX homeobox 1, Homeobox protein BarH like 1,BARX1 (Prognostic Biomarker in Hepatocellular Carcinoma)
Cellular localisation: Nuclear - Molecular Weight
- 24kDa
- Gene ID
- 56033, 164960
- Pathways
- Sensory Perception of Sound
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